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ATP11A Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P98196
Clone Names 90819172
Peptide ID 90819172
Additional Information
Gene ID 23250
Other Names Probable phospholipid-transporting ATPase IH, ATPase IS, ATPase class VI type 11A, P4-ATPase flippase complex alpha subunit ATP11A, ATP11A, ATPIH, ATPIS, KIAA1021
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8755c was selected from the Center region of human ATP11A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATP11A
Synonyms ATPIH, ATPIS, KIAA1021
Function Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). May be involved in the uptake of farnesyltransferase inhibitor drugs, such as lonafarnib.
Cellular Location Cell membrane; Multi-pass membrane protein. Early endosome. Recycling endosome. Endoplasmic reticulum. Note=Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B. In the presence of TMEM30A, predominantly located in the plasma membrane
Research Areas
Citations (0)

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ATP11A is one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex.


Volkmann,N.,, Science 293 (5539), 2456-2459 (2001)

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$ 80.00
Cat# BP8755c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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