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ELMO1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q92556
Clone Names 90723039
Peptide ID 90723039
Additional Information
Gene ID 9844
Other Names Engulfment and cell motility protein 1, Protein ced-12 homolog, ELMO1, KIAA0281
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8761c was selected from the Center region of human ELMO1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ELMO1
Synonyms KIAA0281
Function Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Cellular Location Cytoplasm. Cell membrane. Note=Translocation to plasma membrane seems to be mediated by DOCK1 and CRK
Tissue Location Widely expressed, with a higher expression in the spleen and placenta
Research Areas
Citations (0)

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ELMO1 interacts with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. Similarity to a C. elegans protein suggests that this protein may function in apoptosis and in cell migration.


Choudhary C.,, Science 325:834-840(2009).

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$ 80.00
Cat# BP8761c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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