BHMT2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H2M3 |
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Clone Names | 90826084 |
Gene ID | 23743 |
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Other Names | S-methylmethionine--homocysteine S-methyltransferase BHMT2, SMM-hcy methyltransferase, Betaine--homocysteine S-methyltransferase 2, BHMT2 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8762a was selected from the N-term region of human BHMT2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | BHMT2 |
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Function | Involved in the regulation of homocysteine metabolism. Converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor. |
Tissue Location | Expressed in liver and kidney and at reduced levels in the brain, heart, and skeletal muscle |
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Provided below are standard protocols that you may find useful for product applications.
Background
BHMT2 is involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity).
References
Chadwick L.H., et.al., Genomics 70:66-73(2000).
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