|Other Names||S-methylmethionine--homocysteine S-methyltransferase BHMT2, SMM-hcy methyltransferase, Betaine--homocysteine S-methyltransferase 2, BHMT2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8762a was selected from the N-term region of human BHMT2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the regulation of homocysteine metabolism. Converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor.|
|Tissue Location||Expressed in liver and kidney and at reduced levels in the brain, heart, and skeletal muscle|
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Provided below are standard protocols that you may find useful for product applications.
BHMT2 is involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity).
Chadwick L.H., et.al., Genomics 70:66-73(2000).
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