|Other Names||ATP-dependent RNA helicase DDX50, DEAD box protein 50, Gu-beta, Nucleolar protein Gu2, DDX50|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8763a was selected from the N-term region of human DDX50. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Nucleus, nucleolus|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
DDX50 belongs to the RNA helicase family of proteins involved in unwinding double-stranded RNA during transcription and pre-mRNA splicing, ribosomal RNA synthesis, translation, RNA transport, and RNA stability and degradation. RNA helicases have an Asp-Glu-Ala-Asp (DEAD) motif within the catalytic domain, which gives the family its name (Valdez et al., 2002).
Dephoure N., et.al., Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).Scherl A.,et.al., Mol. Biol. Cell 13:4100-4109(2002).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.