|Other Names||Interleukin-10 receptor subunit alpha, IL-10 receptor subunit alpha, IL-10R subunit alpha, IL-10RA, CDw210a, Interleukin-10 receptor subunit 1, IL-10R subunit 1, IL-10R1, CD210, IL10RA, IL10R|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8768c was selected from the Center region of human IL10RA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for IL10; binds IL10 with a high affinity.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels|
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Provided below are standard protocols that you may find useful for product applications.
IL10RA is a receptor for IL10; binds IL10 with a high affinity.
Jones B.C., et.al., Proc. Natl. Acad. Sci. U.S.A. 99:9404-9409(2002).
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