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GCDH Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q92947
Clone Names 90121133
Peptide ID 90121133
Additional Information
Gene ID 2639
Other Names Glutaryl-CoA dehydrogenase, mitochondrial, GCD, GCDH
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8792a was selected from the N-term region of human GCDH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GCDH
Function Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive.
Cellular Location Mitochondrion matrix.
Tissue Location Isoform Long and isoform Short are expressed in fibroblasts and liver
Research Areas
Citations (0)

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Background

GCDH catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive.

References

Keyser B., et.al., Hum. Mol. Genet. 17:3854-3863(2008).Anikster Y., et.al., Am. J. Hum. Genet. 59:1012-1018(1996).

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$ 80.00
Cat# BP8792a
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