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BIN3 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NQY0 |
|---|---|
| Clone Names | 90504016 |
| Gene ID | 55909 |
|---|---|
| Other Names | Bridging integrator 3, BIN3 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8794a was selected from the N-term region of human BIN3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | BIN3 |
|---|---|
| Function | Involved in cytokinesis and septation where it has a role in the localization of F-actin. |
| Cellular Location | Cytoplasm, cytoskeleton. |
| Tissue Location | Ubiquitously expressed except in brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
BIN3 is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes.
References
Ren,G., et.al., Microbiol. Mol. Biol. Rev. 70 (1), 37-120 (2006)
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