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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   IL18RAP Antibody (N-term) Blocking Peptide   

IL18RAP Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O95256
Clone Names 90429008
Peptide ID 90429008
Additional Information
Gene ID 8807
Other Names Interleukin-18 receptor accessory protein, IL-18 receptor accessory protein, IL-18RAcP, Accessory protein-like, AcPL, CD218 antigen-like family member B, CDw218b, IL-1R accessory protein-like, IL-1RAcPL, Interleukin-1 receptor 7, IL-1R-7, IL-1R7, Interleukin-18 receptor accessory protein-like, Interleukin-18 receptor beta, IL-18R-beta, IL-18Rbeta, CD218b, IL18RAP, IL1R7
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8797a was selected from the N-term region of human IL18RAP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL18RAP (HGNC:5989)
Synonyms IL1R7
Function Within the IL18 receptor complex, does not mediate IL18- binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation (PubMed:9792649, PubMed:14528293, PubMed:25500532). May play a role in IL18- mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable).
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Detected in adrenal gland, bone marrow, brain, fetal brain, fetal liver, heart, kidney, lung, liver, peripheral blood leukocytes, placenta, prostate, salivary gland, skeletal muscle, spinal cord, testis, thymus, thyroid, trachea and uterus (PubMed:17897836). Strongly expressed in peripheral blood leukocytes and spleen and, to a lesser extent, in colon (PubMed:9792649). Specifically coexpressed with IL18R1 in T-helper 1 (Th1)cells (PubMed:10925275, PubMed:11046021, PubMed:10653850)
Research Areas
Citations (0)

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IL18RAP is required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex (By similarity). Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK.


Debets R.,, J. Immunol. 165:4950-4956(2000).

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$ 80.00
Cat# BP8797a
Availability: In Stock
Bulk Size
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