|Other Names||Neutral and basic amino acid transport protein rBAT, NBAT, D2h, Solute carrier family 3 member 1, b(0, +)-type amino acid transport protein, SLC3A1, RBAT|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8802c was selected from the Center region of human SLC3A1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney tubule.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed in the brush border membrane in the kidney (at protein level). Predominantly expressed in the kidney, small intestine and pancreas. Weakly expressed in liver|
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Provided below are standard protocols that you may find useful for product applications.
SLC3A1 is a type II membrane glycoprotein which is one of the components of the renal amino acid transporter which transports neutral and basic amino acids in the renal tubule and intestinal tract.
Chabrol,B., et.al., J. Med. Genet. 45 (5), 314-318 (2008)
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