|Other Names||Tafazzin, Protein G45, TAZ, EFE2, G45|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8803a was selected from the N-term region of human TAZ. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Some isoforms may be involved in cardiolipin (CL) metabolism.|
|Cellular Location||Isoform 1: Membrane; Single-pass membrane protein Isoform 3: Membrane; Single-pass membrane protein Isoform 5: Membrane; Single-pass membrane protein Isoform 7: Membrane; Single-pass membrane protein Isoform 9: Cytoplasm.|
|Tissue Location||High levels in cardiac and skeletal muscle. Up to 10 isoforms can be present in different amounts in different tissues. Most isoforms are ubiquitous. Isoforms that lack the N- terminus are found in leukocytes and fibroblasts, but not in heart and skeletal muscle. Some forms appear restricted to cardiac and skeletal muscle or to leukocytes|
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Provided below are standard protocols that you may find useful for product applications.
TAZ is a protein that is expressed at high levels in cardiac and skeletal muscle.
Gedeon,A.K., et.al., J. Med. Genet. 32 (5), 383-388 (1995)Bione,S., et.al., Nat. Genet. 12 (4), 385-389 (1996)
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