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HIST1H2AH Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96KK5
Other Accession NP_542163
Clone Names 91023153
Peptide ID 91023153
Additional Information
Gene ID 85235
Other Names Histone H2A type 1-H, Histone H2A/s, HIST1H2AH, HIST1H2AI
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8820a was selected from the N-term region of human HIST1H2AH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HIST1H2AI
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Cellular Location Nucleus. Chromosome.
Research Areas
Citations (0)

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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element.


Kimura,H.,, J. Cell Biol. 175 (3), 389-400 (2006)

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$ 80.00
Cat# BP8820a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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