ASPSCR1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9BZE9 |
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Clone Names | 91019008 |
Gene ID | 79058 |
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Other Names | Tether containing UBX domain for GLUT4, Alveolar soft part sarcoma chromosomal region candidate gene 1 protein, Alveolar soft part sarcoma locus, Renal papillary cell carcinoma protein 17, UBX domain-containing protein 9, ASPSCR1, ASPL, RCC17, TUG, UBXD9, UBXN9 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8821b was selected from the C-term region of human ASPSCR1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ASPSCR1 |
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Synonyms | ASPL, RCC17, TUG, UBXD9, UBXN9 |
Function | Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface (By similarity). Enhances VCP methylation catalyzed by VCPKMT. |
Cellular Location | Endomembrane system; Peripheral membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Peripheral membrane protein. Cytoplasm Nucleus |
Tissue Location | Ubiquitous. Highly expressed in testis, heart, skeletal muscle and pancreas. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ASPSCR1 is tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface.
References
Bogan,J.S., et.al., Nature 425 (6959), 727-733 (2003)
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