|Other Names||Dihydropteridine reductase, HDHPR, Quinoid dihydropteridine reductase, QDPR, DHPR|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8841b was selected from the C-term region of human QDPR. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||The product of this enzyme, tetrahydrobiopterin (BH-4), is an essential cofactor for phenylalanine, tyrosine, and tryptophan hydroxylases.|
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Provided below are standard protocols that you may find useful for product applications.
QDPR is the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems.
Schnetz-Boutaud,N.C., et.al.,Genes Brain Behav. 8 (8), 753-757 (2009)
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