|Other Names||Krueppel-like factor 16, Basic transcription element-binding protein 4, BTE-binding protein 4, Novel Sp1-like zinc finger transcription factor 2, Transcription factor BTEB4, Transcription factor NSLP2, KLF16, BTEB4, NSLP2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8855c was selected from the Center region of human KLF16. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that binds GC and GT boxes and displaces Sp1 and Sp3 from these sequences. Modulates dopaminergic transmission in the brain (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
KLF16 is a nuclear zinc finger transcription factor highly expressed in brain regions with abundant dopaminergic terminals, that binds GC and GT boxes and displaces Sp1 and Sp3 from these sequences. KLF16 modulates dopaminergic transmission in the brain.
Parker-Katiraee,L.,et.al., PLoS Genet. 3 (5), E65 (2007)
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