|Other Names||Glycolipid transfer protein, GLTP, GLTP|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8868b was selected from the C-term region of human GLTP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.|
|Tissue Location||Detected in fibroblasts (at protein level). Detected in fibroblasts and in various cancer cell lines|
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Provided below are standard protocols that you may find useful for product applications.
The protein is similar to bovine and porcine proteins which accelerate transfer of certain glycosphingolipids and glyceroglycolipids between membranes. It is thought to be a cytoplasmic protein.
Petersen,N.H.,et.al., FEBS J. 275 (17), 4378-4388 (2008)
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