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DUSP24 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9Y6J8
Clone Names 80311171
Peptide ID 80311171
Additional Information
Gene ID 51657
Other Names Serine/threonine/tyrosine-interacting-like protein 1, Dual specificity phosphatase inhibitor MK-STYX, Dual specificity protein phosphatase 24, Map kinase phosphatase-like protein MK-STYX, STYXL1, DUSP24, MKSTYX
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8875b was selected from the C-term region of human DUSP24. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name STYXL1
Synonyms DUSP24, MKSTYX
Function Probable pseudophosphatase. Contains a Ser residue instead of a conserved Cys residue in the dsPTPase catalytic loop which probably renders it catalytically inactive as a phosphatase. The binding pocket may be however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases.
Research Areas
Citations (0)

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Background

DUSP24 is probable pseudophosphatase. It contains a Ser residue instead of a conserved Cys residue in the dsPTPase catalytic loop which probably renders it catalytically inactive as a phosphatase. The binding pocket may be however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases.

References

Ewing,R.M., et.al., Mol. Syst. Biol. 3, 89 (2007)

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$ 80.00
Cat# BP8875b
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