|Other Names||Zinc finger protein GLIS1, GLI-similar 1, GLIS1 (HGNC:29525)|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8878a was selected from the N-term region of human GLIS1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Acts as both a repressor and activator of transcription. Binds to the consensus sequence 5'-GACCACCCAC-3' (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
GLIS1 is a GLI (MIM 165220)-related Kruppel-like zinc finger protein that functions as an activator and repressor of transcription (Kim et al., 2002 [PubMed 12042312]).
Kim,Y.S., et.al., Nucleic Acids Res. 31 (19), 5513-5525 (2003)Nakanishi,G., et.al., J. Invest. Dermatol. 126 (1), 49-60 (2006)
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