|Other Names||Killer cell immunoglobulin-like receptor 2DL5B, CD158 antigen-like family member F2, Killer cell immunoglobulin-like receptor 2DLX, CD158f2, KIR2DL5B, CD158F, CD158F2, KIR2DL5, KIR2DLX|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8909c was selected from the Center region of human KIR2DL5B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||CD158F, CD158F2, KIR2DL5, KIR2DLX|
|Function||Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
KIR2DL5B is a receptor on natural killer (NK) cells for HLA-C alleles. It inhibits the activity of NK cells thus preventing cell lysis.
Gomez-Lozano N., et.al., Immunogenetics 54:314-319(2002).
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