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FERMT1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BQL6
Clone Names 91009095
Peptide ID 91009095
Additional Information
Gene ID 55612
Other Names Fermitin family homolog 1, Kindlerin, Kindlin syndrome protein, Kindlin-1, Unc-112-related protein 1, FERMT1, C20orf42, KIND1, URP1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8912c was selected from the Center region of human FERMT1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C20orf42, KIND1, URP1
Function Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.
Cellular Location Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Constituent of focal adhesions. Localized at the basal aspect of skin keratinocytes, close to the cell membrane. Colocalizes with filamentous actin Upon TGFB1 treatment, it localizes to membrane ruffles
Tissue Location Expressed in brain, skeletal muscle, kidney, colon, adrenal gland, prostate, and placenta. Weakly or not expressed in heart, thymus, spleen, liver, small intestine, bone marrow, lung and peripheral blood leukocytes. Overexpressed in some colon and lung tumors. In skin, it is localized within the epidermis and particularly in basal keratocytes. Not detected in epidermal melanocytes and dermal fibroblasts
Research Areas
Citations (0)

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FERMT1 is a member of the fermitin family, and contains a FERM domain and a pleckstrin homology domain. This protein is involved in integrin signaling and linkage of the actin cytoskeleton to the extracellular matrix.


Goult B.T.,, J. Mol. Biol. 394:944-956(2009).

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$ 80.00
Cat# BP8912c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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