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CBX1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P83916
Clone Names 91019017
Peptide ID 91019017
Additional Information
Gene ID 10951
Other Names Chromobox protein homolog 1, HP1Hsbeta, Heterochromatin protein 1 homolog beta, HP1 beta, Heterochromatin protein p25, M31, Modifier 1 protein, p25beta, CBX1, CBX
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8915c was selected from the C-term region of human CBX1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CBX1
Synonyms CBX
Function Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
Cellular Location Nucleus. Note=Unassociated with chromosomes during mitosis
Tissue Location Expressed in all adult and embryonic tissues.
Research Areas
Citations (0)

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CBX1 is a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression.


Aagaard,L.,, EMBO J. 18 (7), 1923-1938 (1999)

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$ 80.00
Cat# BP8915c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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