DTD1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8TEA8 |
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Clone Names | 90921140 |
Gene ID | 92675 |
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Other Names | D-tyrosyl-tRNA(Tyr) deacylase 1, 31--, DNA-unwinding element-binding protein B, DUE-B, Histidyl-tRNA synthase-related, DTD1, C20orf88, DUEB, HARS2 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8922b was selected from the C-term region of human DTD1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DTD1 |
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Synonyms | C20orf88, DUEB, HARS2 |
Function | Possible ATPase (PubMed:15653697) involved in DNA replication, may facilitate loading of CDC45 onto pre-replication complexes (PubMed:20065034). |
Cellular Location | Nucleus. Cytoplasm {ECO:0000250|UniProtKB:Q8IIS0} Note=Associated with chromatin at some replication origins containing functional DNA-unwinding elements (PubMed:20065034) |
Tissue Location | Expressed in many adult and fetal tissues. Highest levels in testis, ovary, spleen and in adult and fetal brain |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein is similar in sequence to histidyl-tRNA synthetase, which hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). The encoded protein is found in the cytoplasm.
References
Casper,J.M.,et.al., J. Biol. Chem. 280 (13), 13071-13083 (2005)
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