Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
DTD1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8TEA8 |
|---|---|
| Clone Names | 90921140 |
| Gene ID | 92675 |
|---|---|
| Other Names | D-tyrosyl-tRNA(Tyr) deacylase 1, 31--, DNA-unwinding element-binding protein B, DUE-B, Histidyl-tRNA synthase-related, DTD1, C20orf88, DUEB, HARS2 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8922b was selected from the C-term region of human DTD1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DTD1 |
|---|---|
| Synonyms | C20orf88, DUEB, HARS2 |
| Function | Possible ATPase (PubMed:15653697) involved in DNA replication, may facilitate loading of CDC45 onto pre-replication complexes (PubMed:20065034). |
| Cellular Location | Nucleus. Cytoplasm {ECO:0000250|UniProtKB:Q8IIS0} Note=Associated with chromatin at some replication origins containing functional DNA-unwinding elements (PubMed:20065034) |
| Tissue Location | Expressed in many adult and fetal tissues. Highest levels in testis, ovary, spleen and in adult and fetal brain |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The protein is similar in sequence to histidyl-tRNA synthetase, which hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). The encoded protein is found in the cytoplasm.
References
Casper,J.M.,et.al., J. Biol. Chem. 280 (13), 13071-13083 (2005)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
