RASSF4 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H2L5 |
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Clone Names | 90713239 |
Gene ID | 83937 |
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Other Names | Ras association domain-containing protein 4, RASSF4 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8942c was selected from the Center region of human RASSF4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | RASSF4 |
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Function | Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest. |
Tissue Location | Widely expressed. Frequently down-regulated in tumor cell lines. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of RASSF4 has not yet been determined but it may involve a role in tumor suppression. RASSF4 may act as a KRAS effector protein and may promote apoptosis and cell cycle arrest. Alternative splicing of this gene results in several transcript variants; however, most of the variants have not been fully described.
References
French,D., et.al., Blood 113 (19), 4512-4520 (2009)Grupe,A., et.al., Am. J. Hum. Genet. 78 (1), 78-88 (2006)
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