|Other Names||Lithostathine-1-beta, Pancreatic stone protein 2, PSP-2, Regenerating islet-derived protein 1-beta, REG-1-beta, Regenerating protein I beta, REG1B, PSPS2, REGL|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8946c was selected from the Center region of human REG1B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.|
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Provided below are standard protocols that you may find useful for product applications.
REG1B is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. This protein secreted by the exocrine pancreas that is highly similar to the REG1A protein. The related REG1A protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis.
Usami,S., et.al., Biochem. Biophys. Res. Commun. 392 (1), 4-8 (2010)Banchuin,N., et.al., Diabetes Res. Clin. Pract. 55 (2), 105-111 (2002)
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