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CDC5L Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q99459
Clone Names 90904035
Peptide ID 90904035
Additional Information
Gene ID 988
Other Names Cell division cycle 5-like protein, Cdc5-like protein, Pombe cdc5-related protein, CDC5L, KIAA0432, PCDC5RP
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8949c was selected from the Center region of human CDC5L. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDC5L
Synonyms KIAA0432, PCDC5RP
Function DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Cellular Location Nucleus. Nucleus speckle. Cytoplasm. Note=May shuttle between cytoplasm and nucleus.
Tissue Location Ubiquitously expressed in both fetal and adult tissues.
Research Areas
Citations (0)

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The protein is a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.


Grillari,J.,, J. Biol. Chem. 284 (42), 29193-29204 (2009)Zhang,N.,, EMBO Rep. 10 (9), 1029-1035 (2009)

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$ 80.00
Cat# BP8949c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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