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CNKSR3 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6P9H4 |
|---|---|
| Clone Names | 90904111 |
| Gene ID | 154043 |
|---|---|
| Other Names | Connector enhancer of kinase suppressor of ras 3, Connector enhancer of KSR 3, CNK homolog protein 3, CNK3, CNKSR family member 3, Maguin-like protein, CNKSR3, MAGI1 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8957b was selected from the C-term region of human CNKSR3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CNKSR3 |
|---|---|
| Synonyms | MAGI1 |
| Function | Involved in transepithelial sodium transport. Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport through regulation of ENaC cell surface expression. Acts as a scaffold protein coordinating the assembly of an ENaC- regulatory complex (ERC). |
| Cellular Location | Cytoplasm. Apical cell membrane; Peripheral membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
CNKSR3 belongs to the CNKSR family. It contains 1 CRIC domain, 1 DUF1170 domain, 1 PDZ (DHR) domain and 1 SAM (sterile alpha motif) domain.
References
Ziera,T., et.al., FASEB J. 23 (11), 3936-3946 (2009)
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