|Other Names||Glutathione S-transferase A4, GST class-alpha member 4, Glutathione S-transferase A4-4, GSTA4|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8970a was selected from the N-term region of human GSTA4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4- hydroxynonenal (4-HNE).|
|Tissue Location||Expressed at a high level in brain, placenta, and skeletal muscle and much lower in lung and liver|
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Provided below are standard protocols that you may find useful for product applications.
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4-hydroxynonenal (4-HNE).
Bruns C.M.,et.al., J. Mol. Biol. 288:427-439(1999).
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