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SLC12A3 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P55017
Clone Names 90723115
Peptide ID 90723115
Additional Information
Gene ID 6559
Other Names Solute carrier family 12 member 3, Na-Cl cotransporter, NCC, Na-Cl symporter, Thiazide-sensitive sodium-chloride cotransporter, SLC12A3, NCC, TSC
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8971c was selected from the Center region of human SLC12A3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC12A3
Synonyms NCC, TSC
Function Key mediator of sodium and chloride reabsorption in this nephron segment, accounting for a significant fraction of renal sodium reabsorption.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Predominant in kidney.
Research Areas
Citations (0)

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Background

SLC12A3 is a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule.

References

Mastroianni,N.,et.al., Genomics 35 (3), 486-493 (1996)Simon,D.B., et.al., Nat. Genet. 12 (1), 24-30 (1996)

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$ 80.00
Cat# BP8971c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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