|Other Names||L-serine dehydratase/L-threonine deaminase, SDH, L-serine deaminase, L-threonine dehydratase, TDH, SDS, SDH|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9041a was selected from the N-term region of human SDS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
SDS encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver.
Yamada,T., et.al., Biochim. Biophys. Acta 1780 (5), 809-818 (2008)Szaflik,J.P., et.al., Exp. Eye Res. 86 (4), 647-652 (2008)
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