|Other Names||[Protein ADP-ribosylarginine] hydrolase-like protein 1, 32--, ADP-ribosylhydrolase 2, ADPRHL1, ARH2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9063a was selected from the N-term region of human ADPRHL1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
ADPRHL1 is a reversible posttranslational modification used to regulate protein function. ADP-ribosyltransferases (see ART1; MIM 601625) transfer ADP-ribose from NAD+ to the target protein, and ADP-ribosylhydrolases, such as ADPRHL1, reverse the reaction.
Dunham,A., et.al., Nature 428 (6982), 522-528 (2004)Glowacki,G., et.al., Protein Sci. 11 (7), 1657-1670 (2002)
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