AGMAT Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9BSE5 |
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Clone Names | 90819075 |
Gene ID | 79814 |
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Other Names | Agmatinase, mitochondrial, Agmatine ureohydrolase, AUH, AGMAT |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9064a was selected from the N-term region of human AGMAT. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | AGMAT |
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Synonyms | GDAH {ECO:0000303|PubMed:36543883} |
Function | Hydrolyzes linear guanidino acids to form urea and the corresponding amines. Displays specificity for substrates having a negatively charged head group and short chains including taurocyamine, guanidino propanoic and butanoic acids. May protect cells by detoxifying potentially harmful amounts of guanidino acids. Metabolizes L-arginine with low efficiency. |
Cellular Location | Mitochondrion. |
Tissue Location | Highly expressed in liver and kidney. Also found in skeletal muscle, fetal liver, brain, testis, skin and the gastrointestinal tract. Within brain, expression is higher in the cerebral cortex with lower levels in the medulla and spinal cord |
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Provided below are standard protocols that you may find useful for product applications.
References
Kim,K.H., et.al., Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 61 (PT 10), 889-891 (2005)Dallmann,K., et.al., Int. J. Cancer 108 (3), 342-347 (2004)
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