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ARRDC4 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8NCT1
Clone Names 90819160
Additional Information
Gene ID 91947
Other Names Arrestin domain-containing protein 4, ARRDC4
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9068c was selected from the Center region of human ARRDC4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARRDC4
Function Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (By similarity). Plays a role in endocytosis of activated G protein-coupled receptors (GPCRs) (Probable). Through an ubiquitination-dependent mechanism also plays a role in the incorporation of SLC11A2 into extracellular vesicles (By similarity). May play a role in glucose uptake (PubMed:19605364). Participates in innate immune response by promoting IFIH1/MDA5 activation through interaction with TRIM65 (PubMed:28594402).
Cellular Location Early endosome. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Note=Also found in extracellular vesicles different from exosomes. {ECO:0000250|UniProtKB:A0A0B4J1F4}
Research Areas
Citations (0)
citation

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References

Patwari,P., et.al., J. Biol. Chem. 284 (37), 24996-25003 (2009)Knoll,B., et.al., Genet. Test. 12 (1), 147-152 (2008)

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$ 277.78
Cat# BP9068c
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Availability: 2 weeks
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