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ACR Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P10323
Clone Names 80305111
Additional Information
Gene ID 49
Other Names Acrosin, Acrosin light chain, Acrosin heavy chain, ACR, ACRS
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9079c was selected from the Center region of human ACR. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACR
Synonyms ACRS
Function Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.
Research Areas
Citations (0)
citation

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Background

ACR is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.

References

Dube,C., et.al., J. Androl. 26 (4), 519-528 (2005)Furlong,L.I., et.al., Fertil. Steril. 83 (6), 1791-1796 (2005)

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$ 277.78
Cat# BP9079c
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Availability: 2 weeks
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