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KIF11 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P52732
Clone Names 90723069
Peptide ID 90723069
Additional Information
Gene ID 3832
Other Names Kinesin-like protein KIF11, Kinesin-like protein 1, Kinesin-like spindle protein HKSP, Kinesin-related motor protein Eg5, Thyroid receptor-interacting protein 5, TR-interacting protein 5, TRIP-5, KIF11, EG5, KNSL1, TRIP5
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9097a was selected from the N-term region of human KIF11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KIF11
Synonyms EG5, KNSL1, TRIP5
Function Motor protein required for establishing a bipolar spindle during mitosis (PubMed:19001501). Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface (PubMed:23857769).
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton, spindle pole
Research Areas
Citations (0)

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Background

KIF11 belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis.

References

Tcherniuk,S., et.al., Biochem. Pharmacol. 79 (6), 864-872 (2010)Parke,C.L., et.al., J. Biol. Chem. 285 (8), 5859-5867 (2010)

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$ 80.00
Cat# BP9097a
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