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C14orf133 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9H9C1
Clone Names 90826108
Additional Information
Gene ID 63894
Other Names Spermatogenesis-defective protein 39 homolog, hSPE-39, VPS33B-interacting protein in apical-basolateral polarity regulator, VPS33B-interacting protein in polarity and apical restriction, VIPAS39, C14orf133, SPE39, VIPAR
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9104c was selected from the Center region of human C14orf133. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name VIPAS39
Synonyms C14orf133, SPE39, VIPAR
Function Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753). May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be independent of VPS33B (PubMed:19109425). May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or indirect transcriptional regulation of E-cadherin (By similarity).
Cellular Location Cytoplasm. Cytoplasmic vesicle. Early endosome. Recycling endosome Late endosome. Note=Colocalizes in clusters with VPS33B at cytoplasmic organelles (PubMed:19109425)
Research Areas
Citations (0)
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References

Zhu,G.D., et.al., Mol. Biol. Cell 20 (4), 1223-1240 (2009)Rush,J., et.al., Nat. Biotechnol. 23 (1), 94-101 (2005)

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$ 277.78
Cat# BP9104c
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