TSPAN4 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O14817 |
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Clone Names | 90909155 |
Gene ID | 7106 |
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Other Names | Tetraspanin-4, Tspan-4, Novel antigen 2, NAG-2, Transmembrane 4 superfamily member 7, TSPAN4, NAG2, TM4SF7 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9152c was selected from the Center region of human TSPAN4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TSPAN4 |
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Synonyms | NAG2, TM4SF7 |
Cellular Location | Membrane; Multi-pass membrane protein. |
Tissue Location | Expressed in multiple tissues but is absent in brain, lymphoid cells, and platelets |
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Provided below are standard protocols that you may find useful for product applications.
Background
TSPAN4 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins.
References
Sjoeblom T., et.al., Science 314:268-274(2006).
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