|Other Names||Tetraspanin-4, Tspan-4, Novel antigen 2, NAG-2, Transmembrane 4 superfamily member 7, TSPAN4, NAG2, TM4SF7|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9152c was selected from the Center region of human TSPAN4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in multiple tissues but is absent in brain, lymphoid cells, and platelets|
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Provided below are standard protocols that you may find useful for product applications.
TSPAN4 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins.
Sjoeblom T., et.al., Science 314:268-274(2006).
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