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HIST1H1C Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P16403
Clone Names 90504066
Peptide ID 90504066
Additional Information
Gene ID 3006
Other Names Histone H12, Histone H1c, Histone H1d, Histone H1s-1, HIST1H1C, H1F2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9164c was selected from the Center region of human HIST1H1C. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HIST1H1C
Synonyms H1F2
Function Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
Cellular Location Nucleus. Chromosome. Note=Mainly localizes in euchromatin. Distribution goes in parallel with DNA concentration
Research Areas
Citations (0)

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Background

Histones H1 are necessary for the condensation of nucleosome chains into higher order structures.

References

Mayya V., et.al., Sci. Signal. 2:RA46-RA46(2009).

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$ 80.00
Cat# BP9164c
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