|Other Names||Beta-Ala-His dipeptidase, CNDP dipeptidase 1, Carnosine dipeptidase 1, Glutamate carboxypeptidase-like protein 2, Serum carnosinase, CNDP1, CN1, CPGL2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9166b was selected from the C-term region of human CNDP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Found in serum and adult nervous central system. Absent in serum from patients with homocarnosinosis|
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Provided below are standard protocols that you may find useful for product applications.
CNDP1 encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This protein contains trinucleotide (CTG) repeat length polymorphism in the coding region.
Craig,D.W., et.al., Diabet. Med. 26 (11), 1090-1098 (2009)Mooyaart,A.L., et.al., Diabetes Res. Clin. Pract. 85 (3), 272-278 (2009)
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