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CNDP1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q96KN2 |
|---|---|
| Clone Names | 90713049 |
| Gene ID | 84735 |
|---|---|
| Other Names | Beta-Ala-His dipeptidase, CNDP dipeptidase 1, Carnosine dipeptidase 1, Glutamate carboxypeptidase-like protein 2, Serum carnosinase, CNDP1, CN1, CPGL2 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9166b was selected from the C-term region of human CNDP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CNDP1 (HGNC:20675) |
|---|---|
| Synonyms | CN1, CPGL2 |
| Function | Catalyzes the peptide bond hydrolysis in Xaa-His dipeptides, displaying the highest activity toward carnosine (beta-alanyl-L- histidine) and anserine (beta-alanyl-3-methyl-histidine). |
| Cellular Location | Secreted. |
| Tissue Location | Found in serum and adult nervous central system. Absent in serum from patients with homocarnosinosis |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
CNDP1 encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This protein contains trinucleotide (CTG) repeat length polymorphism in the coding region.
References
Craig,D.W., et.al., Diabet. Med. 26 (11), 1090-1098 (2009)Mooyaart,A.L., et.al., Diabetes Res. Clin. Pract. 85 (3), 272-278 (2009)
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