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PHTF1 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9UMS5
Clone Names 90723099
Peptide ID 90723099
Additional Information
Other Names Putative homeodomain transcription factor 1, PHTF1, PHTF
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9167c was selected from the Center region of human PHTF1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PHTF1
Synonyms PHTF
Function May play a role in transcription regulation.
Cellular Location Nucleus.
Tissue Location Widely expressed with highest levels in testis. EMBL; AJ011863; CAB51572.1; -; mRNA EMBL; AL365321; CAH72504.1; -; Genomic_DNA EMBL; AL133517; CAH72504.1; JOINED; Genomic_DNA EMBL; AL133517; CAI22549.1; -; Genomic_DNA EMBL; AL365321; CAI22549.1; JOINED; Genomic_DNA EMBL; AL365321; CAH72503.1; -; Genomic_DNA EMBL; AL133517; CAH72503.1; JOINED; Genomic_DNA EMBL; AL133517; CAI22547.1; -; Genomic_DNA EMBL; AL365321; CAI22547.1; JOINED; Genomic_DNA EMBL; BC002447; AAH02447.1; -; mRNA CCDS; CCDS81359.1; -. [Q9UMS5-2] CCDS; CCDS861.1; -. [Q9UMS5-1] RefSeq; NP_001309970.1; NM_001323041.1. [Q9UMS5-1] RefSeq; NP_001309971.1; NM_001323042.1. [Q9UMS5-1] RefSeq; NP_001309972.1; NM_001323043.1. [Q9UMS5-1] RefSeq; NP_001309976.1; NM_001323047.1. [Q9UMS5-2] RefSeq; NP_001309977.1; NM_001323048.1. [Q9UMS5-2] RefSeq; NP_001309978.1; NM_001323049.1. [Q9UMS5-2] RefSeq; NP_006599.2; NM_006608.2. [Q9UMS5-1] UniGene; Hs.655824; - ProteinModelPortal; Q9UMS5; - SMR; Q9UMS5; - BioGrid; 115968; 4 IntAct; Q9UMS5; 1 STRING; 9606.ENSP00000358617; - iPTMnet; Q9UMS5; - PhosphoSitePlus; Q9UMS5; - BioMuta; PHTF1; - DMDM; 71152973; - EPD; Q9UMS5; - PaxDb; Q9UMS5; - PeptideAtlas; Q9UMS5; - PRIDE; Q9UMS5; - Ensembl; ENST00000357783; ENSP00000350428; ENSG00000116793. [Q9UMS5-2] Ensembl; ENST00000369604; ENSP00000358617; ENSG00000116793. [Q9UMS5-1] Ensembl; ENST00000393357; ENSP00000377025; ENSG00000116793. [Q9UMS5-1] GeneID; 10745; - KEGG; hsa:10745; - UCSC; uc001edn.4; human. [Q9UMS5-1] CTD; 10745; - DisGeNET; 10745; - GeneCards; PHTF1; - HGNC; HGNC:8939; PHTF1 HPA; HPA059486; - MIM; 604950; gene neXtProt; NX_Q9UMS5; - OpenTargets; ENSG00000116793; - PharmGKB; PA33278; - eggNOG; ENOG410IF1F; Eukaryota eggNOG; ENOG410ZM0V; LUCA GeneTree; ENSGT00390000011648; - HOGENOM; HOG000030907; - HOVERGEN; HBG061164; - InParanoid; Q9UMS5; - OMA; GEAQTQM; - OrthoDB; EOG091G0334; - PhylomeDB; Q9UMS5; - TreeFam; TF323570; - BioCyc; ZFISH:ENSG00000116793-MONOMER; - GenomeRNAi; 10745; - PRO; PR:Q9UMS5; - Proteomes; UP000005640; Chromosome 1 Bgee; ENSG00000116793; - CleanEx; HS_PHTF1; - ExpressionAtlas; Q9UMS5; baseline and differential Genevisible; Q9UMS5; HS GO; GO:0005801; C:cis-Golgi network; IEA:Ensembl GO; GO:0005737; C:cytoplasm; IDA:HPA GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl GO; GO:0005730; C:nucleolus; IDA:HPA GO; GO:0005634; C:nucleus; IDA:HPA GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; TAS:ProtInc GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW InterPro; IPR021980; TF_homeodomain_male Pfam; PF12129; Phtf-FEM1B_bdg; 1 2: Evidence at transcript level; Alternative splicing; Complete proteome; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation CHAIN 1 762 Putative homeodomain transcription factor 1 /FTId=PRO_0000127423 MOD_RES 272 272 Phosphoserine {ECO:0000250|UniProtKB:Q9QZ09} MOD_RES 276 276 Phosphoserine {ECO:0000250|UniProtKB:Q9QZ09} MOD_RES 277 277 Phosphoserine {ECO:0000250|UniProtKB:Q9QZ09} MOD_RES 334 334 Phosphoserine {ECO:0000250|UniProtKB:Q9QZ09} MOD_RES 336 336 Phosphoserine {ECO:0000250|UniProtKB:Q9QZ09} VAR_SEQ 632 637 LQGHKT -> KVSHLL (in isoform 2) /FTId=VSP_002144 VAR_SEQ 638 762 Missing (in isoform 2) /FTId=VSP_002145 CONFLICT 245 245 W -> C (in Ref. 1; CAB51572) CONFLICT 251 251 A -> P (in Ref. 1; CAB51572) CONFLICT 518 518 C -> G (in Ref. 1; CAB51572) CONFLICT 529 529 L -> W (in Ref. 1; CAB51572) CONFLICT 638 638 F -> S (in Ref. 1; CAB51572) SEQUENCE 762 AA; 87252 MW; 0813B7A668262DD9 CRC64; MASNERDAIS WYQKKIGAYD QQIWEKSIEQ TQIKGLKNKP KKMGHIKPDL IDVDLIRGST FAKAKPEIPW TSLTRKGLVR VVFFPLFSNW WIQVTSLRIF VWLLLLYFMQ VIAIVLYLMM PIVNISEVLG PLCLMLLMGT VHCQIVSTQI TRPSGNNGNR RRRKLRKTVN GDGSRENGNN SSDKVRGIET LESVPIIGGF WETIFGNRIK RVKLISNKGT ETDNDPSCVH PIIKRRQCRP EIRMWQTREK AKFSDGEKCR REAFRRLGNG VSDDLSSEED GEARTQMILL RRSVEGASSD NGCEVKNRKS ILSRHLNSQV KKTTTRWCHI VRDSDSLAES EFESAAFSQG SRSGVSGGSR SLNMSRRDSE STRHDSETED MLWDDLLHGP ECRSSVTSDS EGAHVNTLHS GTKRDPKEDV FQQNHLFWLQ NSSPSSDRVS AIIWEGNECK KMDMSVLEIS GIIMSRVNAY QQGVGYQMLG NVVTIGLAFF PFLHRLFREK SLDQLKSISA EEILTLFCGA PPVTPIIVLS IINFFERLCL TWMFFFMMCV AERTYKQRFL FAKLFSHITS ARKARKYEIP HFRLKKVENI KIWLSLRSYL KRRGPQRSVD VVVSSVFLLT LSIAFICCAQ VLQGHKTFLN DAYNWEFLIW ETALLLFLLR LASLGSETNK KYSNVSILLT EQINLYLKME KKPNKKEQLT LVNNVLKLST KLLKELDTPF RLYGLTMNPL IYNITRVVIL SAVSGVISDL LGFNIRLWKI KS
Research Areas
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Background

PHTF1 may play a role in transcription regulation.

References

Douroudis,K., et.al., BMC Med. Genet. 11, 11 (2010)Cooper,J.D., et.al., Nat. Genet. 40 (12), 1399-1401 (2008)

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$ 80.00
Cat# BP9167c
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