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KCNH7 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NS40
Clone Names 90805054
Additional Information
Gene ID 90134
Other Names Potassium voltage-gated channel subfamily H member 7, Ether-a-go-go-related gene potassium channel 3, ERG-3, Eag-related protein 3, Ether-a-go-go-related protein 3, hERG-3, Voltage-gated potassium channel subunit Kv113, KCNH7, ERG3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9169a was selected from the N-term region of human KCNH7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCNH7
Synonyms ERG3
Function Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Expressed in prolactin-secreting adenomas.
Research Areas
Citations (0)
citation

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Background

KCNH7 represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This protein encodes a member of the potassium channel, voltage-gated, subfamily H.

References

Alkelai,A., et.al., Psychopharmacology (Berl.) 206 (3), 491-499 (2009)Couturier,N., et.al., Eur. J. Hum. Genet. 17 (6), 844-847 (2009)

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$ 277.78
Cat# BP9169a
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