|Other Names||Inositol hexakisphosphate kinase 2, InsP6 kinase 2, P(i)-uptake stimulator, PiUS, IP6K2, IHPK2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9185c was selected from the Center region of human IP6K2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.|
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Provided below are standard protocols that you may find useful for product applications.
IP6K2 belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers.
Morrison,B.H., et.al., J. Biol. Chem. 282 (21), 15349-15356 (2007)Nagata,E., et.al., J. Biol. Chem. 280 (2), 1634-1640 (2005)
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