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DHRS3 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O75911
Clone Names 90921108
Additional Information
Gene ID 9249
Other Names Short-chain dehydrogenase/reductase 3, DD831, Retinal short-chain dehydrogenase/reductase 1, retSDR1, DHRS3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9188c was selected from the Center region of human DHRS3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DHRS3
Synonyms RDH17, SDR16C1
Function Catalyzes the reduction of all-trans-retinal to all-trans- retinol in the presence of NADPH.
Cellular Location Membrane; Multi-pass membrane protein
Tissue Location Widely expressed with highest levels found in heart, placenta, lung, liver, kidney, pancreas, thyroid, testis, stomach, trachea and spinal cord. Lower levels found in skeletal muscle, intestine and lymph node. No expression detected in brain. In the retina, expressed in cone but not rod outer segments
Research Areas
Citations (0)
citation

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Background

DHRS3 catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids.

References

Persson,B., et.al., Chem. Biol. Interact. 178 (1-3), 94-98 (2009)Roni,V., et.al., BMC Genomics 8, 42 (2007)

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$ 277.78
Cat# BP9188c
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