|Other Names||Alcohol dehydrogenase 6, ADH6|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9203c was selected from the Center region of human ADH6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Stomach and liver.|
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Provided below are standard protocols that you may find useful for product applications.
ADH6 encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This protein is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site.
Cui,R., et.al., Gastroenterology 137 (5), 1768-1775 (2009)Saito,A., et.al., J. Hum. Genet. 54 (6), 317-323 (2009)Tabakoff,B., et.al., BMC Biol. 7, 70 (2009)
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