S39A3 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9BRY0 |
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Clone Names | 91109131 |
Gene ID | 29985 |
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Other Names | Zinc transporter ZIP3, Solute carrier family 39 member 3, Zrt- and Irt-like protein 3, ZIP-3, SLC39A3, ZIP3 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9206c was selected from the Center region of human S39A3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SLC39A3 (HGNC:17128) |
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Synonyms | ZIP3 |
Function | Transporter for the divalent cation Zn(2+). Mediates the influx of Zn(2+) into cells from extracellular space. Controls Zn(2+) accumulation into dentate gyrus granule cells in the hippocampus. Mediates Zn(2+) reuptake from the secreted milk within the alveolar lumen. |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q99K24}; Multi-pass membrane protein. Apical cell membrane {ECO:0000250|UniProtKB:Q99K24}; Multi-pass membrane protein. Note=Localized primarily at the cell surface but also found in a perinuclear compartment in HC11 cells. In mammary epithelial cell, localized primary to the apical membrane {ECO:0000250|UniProtKB:Q99K24} |
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Provided below are standard protocols that you may find useful for product applications.
References
Ollila,H.M., et.al., Mol. Psychiatry 14 (4), 351-353 (2009)Kahmann,L., et.al, Rejuvenation Res 11 (1), 227-237 (2008)
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