|Other Names||MARVEL domain-containing protein 2, Tricellulin, MARVELD2, TRIC|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9219b was selected from the C-term region of human MALD2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the formation of the epithelial barriers. The separation of the endolymphatic and perilymphatic spaces of the organ of Corti from one another by epithelial barriers is required for normal hearing.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Cell junction, tight junction. Note=Found at tricellular contacts.|
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Provided below are standard protocols that you may find useful for product applications.
MALD2 plays a role in the formation of the epithelial barriers. The separation of the endolymphatic and perilymphatic spaces of the organ of Corti from one another by epithelial barriers is required for normal hearing.
Tam,S., et.al., Nat. Struct. Mol. Biol. 16 (12), 1279-1285 (2009)Krug,S.M., et.al., Mol. Biol. Cell 20 (16), 3713-3724 (2009)
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