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MALD2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8N4S9 |
|---|---|
| Clone Names | 91109098 |
| Gene ID | 153562 |
|---|---|
| Other Names | MARVEL domain-containing protein 2, Tricellulin, MARVELD2, TRIC |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9219b was selected from the C-term region of human MALD2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MARVELD2 (HGNC:26401) |
|---|---|
| Synonyms | TRIC |
| Function | Plays a role in the formation of tricellular tight junctions and of epithelial barriers (By similarity). Required for normal hearing via its role in the separation of the endolymphatic and perilymphatic spaces of the organ of Corti in the inner ear, and for normal survival of hair cells in the organ of Corti (PubMed:17186462). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Cell junction, tight junction. Note=Located at tricellular contacts. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
MALD2 plays a role in the formation of the epithelial barriers. The separation of the endolymphatic and perilymphatic spaces of the organ of Corti from one another by epithelial barriers is required for normal hearing.
References
Tam,S., et.al., Nat. Struct. Mol. Biol. 16 (12), 1279-1285 (2009)Krug,S.M., et.al., Mol. Biol. Cell 20 (16), 3713-3724 (2009)
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