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C20orf72 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BQP7
Clone Names 90826152
Peptide ID 90826152
Additional Information
Gene ID 92667
Other Names Mitochondrial genome maintenance exonuclease 1 {ECO:0000255|HAMAP-Rule:MF_03030}, 31-- {ECO:0000255|HAMAP-Rule:MF_03030}, MGME1 {ECO:0000255|HAMAP-Rule:MF_03030}, C20orf72, DDK1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9240c was selected from the Center region of human C20orf72. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MGME1 {ECO:0000255|HAMAP-Rule:MF_03030}
Synonyms C20orf72, DDK1
Function Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.
Cellular Location Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03030, ECO:0000269|PubMed:23313956, ECO:0000269|PubMed:23358826}
Research Areas
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Deloukas,P.,, Nature 414 (6866), 865-871 (2001)

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$ 80.00
Cat# BP9240c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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