BEST2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8NFU1 |
---|---|
Clone Names | 91204007 |
Gene ID | 54831 |
---|---|
Other Names | Bestrophin-2, Vitelliform macular dystrophy 2-like protein 1, BEST2, VMD2L1 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9246b was selected from the C-term region of human BEST2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | BEST2 |
---|---|
Synonyms | VMD2L1 |
Function | Forms calcium-sensitive chloride channels. Permeable to bicarbonate. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Mainly confined to the retinal pigment epithelium and colon. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
BEST2 is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif.
References
Zhang,Y., et.al, Mol. Vis. 16, 200-206 (2010)Marsey,L.L. et.al, J. Physiol. (Lond.) 587 (PT 10), 2211-2224 (2009)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.