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BEST2 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8NFU1
Clone Names 91204007
Additional Information
Gene ID 54831
Other Names Bestrophin-2, Vitelliform macular dystrophy 2-like protein 1, BEST2, VMD2L1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9246b was selected from the C-term region of human BEST2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BEST2
Synonyms VMD2L1
Function Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Mainly confined to the retinal pigment epithelium and colon.
Research Areas
Citations (0)
citation

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Background

BEST2 is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif.

References

Zhang,Y., et.al, Mol. Vis. 16, 200-206 (2010)Marsey,L.L. et.al, J. Physiol. (Lond.) 587 (PT 10), 2211-2224 (2009)

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$ 277.78
Cat# BP9246b
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