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RAT MIF Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P30904
Clone Names 91204013
Peptide ID 91204013
Additional Information
Gene ID 103694877;81683
Other Names Macrophage migration inhibitory factor, MIF, Glutathione-binding 13 kDa protein, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase, Mif
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9249b was selected from the C-term region of human RAT MIF. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Mif
Function Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti- inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity (By similarity).
Cellular Location Secreted. Cytoplasm. Note=Does not have a cleavable signal sequence and is secreted via a specialized, non-classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens (By similarity)
Tissue Location Expressed in a wide variety of organs including brain, spleen, liver, muscle and kidney
Research Areas
Citations (0)

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RAT MIF inhibits random migration of macrophages and is involved in the pathogenesis of several inflammatory diseases.


Harrison,R.A., Biochem. Biophys. Res. Commun. 390 (1), 171-175 (2009)Jian,Z.,, Clin. Chim. Acta 405 (1-2), 132-138 (2009)

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$ 80.00
Cat# BP9249b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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