ACTR5 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H9F9 |
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Clone Names | 90723133 |
Gene ID | 79913 |
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Other Names | Actin-related protein 5, hARP5, Sarcoma antigen NY-SAR-16, ACTR5, ARP5 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9266b was selected from the C-term region of human ACTR5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ACTR5 |
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Synonyms | ARP5 |
Function | Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Involved in DNA double-strand break repair and UV-damage excision repair. |
Cellular Location | Nucleus. Cytoplasm. Note=Predominantly nuclear but undergoes nucleo-cytoplasmic shuttling (PubMed:19014934). Localized to interphase nuclei, but not nucleoli; excluded from chromosomes as mitosis progresses (PubMed:18163988) |
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Provided below are standard protocols that you may find useful for product applications.
Background
ACTR5 may be involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex
References
Kitayama,K., et.al, Exp. Cell Res. 315 (2), 206-217 (2009)Jin,J., et.al, J. Biol. Chem. 280 (50), 41207-41212 (2005)Lee,S.Y., et.al, Proc. Natl. Acad. Sci. U.S.A. 100 (5), 2651-2656 (2003)
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