|Other Names||Peroxisomal targeting signal 1 receptor, PTS1 receptor, PTS1R, PTS1-BP, Peroxin-5, Peroxisomal C-terminal targeting signal import receptor, Peroxisome receptor 1, PEX5, PXR1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9268c was selected from the Center region of human PEX5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.|
|Cellular Location||Cytoplasm. Peroxisome membrane; Peripheral membrane protein. Note=Its distribution appears to be dynamic. It is probably a cycling receptor found mainly in the cytoplasm and as well associated to the peroxisomal membrane through a docking factor (PEX13)|
|Tissue Location||Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
PEX5 binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
Alencastre,I.S., et.al, J. Biol. Chem. 284 (40), 27243-27251 (2009)Shiozawa,K., et.al, J. Biol. Chem. 284 (37), 25334-25342 (2009)Grou,C.P., et.al, J. Biol. Chem. 284 (16), 10504-10513 (2009)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.