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XDH Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P47989
Clone Names 90909112
Peptide ID 90909112
Additional Information
Gene ID 7498
Other Names Xanthine dehydrogenase/oxidase, Xanthine dehydrogenase, XD, Xanthine oxidase, XO, Xanthine oxidoreductase, XOR, XDH, XDHA
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9277a was selected from the N-term region of human XDH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name XDH
Synonyms XDHA
Function Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).
Cellular Location Cytoplasm. Peroxisome. Secreted
Tissue Location Detected in milk (at protein level). {ECO:0000269|Ref.12}
Research Areas
Citations (0)

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XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. This protein can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.


Ross,C.J.,, Nat. Genet. 41 (12), 1345-1349 (2009)Taibi,G.,, J. Cell. Biochem. 108 (3), 688-692 (2009)Spiekermann,S.,, Eur. Respir. J. 34 (1), 276 (2009)

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$ 80.00
Cat# BP9277a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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